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Spinocerebellar ataxia type 1

This video demonstrates a 55-year-old woman with spinocerebellar ataxia type 1. She presents with progressive ataxia for over 10 years. There is prominent facial masking. Her speech is slurred and has scanning quality. Eye movement examination reveals limited upgaze whereas saccadic velocity is relatively preserved (not shown). There is also mild reduction of vibratory sensation in the ankles. (Contributed by Dr. Pichet Termsarasab.)