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Muscle biopsy in Becker muscular dystrophy (2)

Immunostaining against the N-terminal region of the dystrophin molecule shows patchy and uneven staining; some fibers have no dystrophin staining (A). Immunostaining against the rod-portion of the dystrophin molecule in the same patient is remarkably preserved (B). Dystrophin immunohistochemistry. (Contributed by Dr. Andrew Waclawik.)

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Associated Disorders

  • Becker muscular dystrophy
  • CIDP
  • Charcot-Marie-Tooth disease
  • Duchenne muscular dystrophy
  • Kearns-Sayre syndrome
  • Kugelberg-Welander disease
  • MELAS
  • MERRF
  • McArdle disease
  • Miyoshi distal myopathy
  • NARP
  • Nonaka distal myopathy
  • Stormorken syndrome
  • Welander distal myopathy
  • Werdnig-Hoffman disease
  • acid maltase deficiency
  • amyloidosis
  • carnitine palmitoyltransferase deficiency
  • central core disease
  • centronuclear myopathy
  • congenital fiber-type disproportion
  • cysticercosis
  • denervation atrophy
  • dermatomyositis
  • facioscapulohumeral muscular dystrophy
  • hereditary neuropathy with pressure palsy
  • inclusion-body myositis
  • leprous neuropathy
  • limb-girdle muscular dystrophy
  • myotubular myopathy
  • nemaline rod myopathy
  • peripheral nerve vasculitis
  • polymyositis
  • progressive external ophthalmoplegia
  • sarcoid myopathy
  • sarcoid neuropathy
  • spinal muscular atrophy
  • toxoplasmosis
  • trichinellosis
  • tubular aggregates myopathy