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Central auditory deficits associated with different genetic forms of peripheral deafness

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The central auditory deficits shown in orange constitute an ensemble of indirect effects presumably common to all forms of congenital peripheral deafness. Other central deficits in blue denote deficits that may be combined in specific genetic forms of congenital deafness. Except for genes playing intrinsic roles in both the central and peripheral auditory systems, all central auditory deficits shown here are indirect consequences of peripheral hearing impairment. The time scale is based on the development of the human auditory system. (Source: Michalski N, Petit C. Central auditory deficits associated with genetic forms of peripheral deafness. Hum Genet 2022;141(3-4):335-45. Creative Commons Attribution 4.0 International License. http://creativecommons.org/licenses/by/4.0.)