Developmental Malformations
Holoprosencephaly
Nov. 05, 2023
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Toll Free (U.S. + Canada): 800-452-2400
US Number: +1-619-640-4660
Support: service@medlink.com
Editor: editor@medlink.com
ISSN: 2831-9125
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Brain MRI at the age of 12 years, at the time of the initial attack. (A1) T2-weighted axial MRI showing a large parietal lesion with edema and mass effect. The lesion is surrounded by a hypointense rim. (A2) T1-weighted axial MRI with gadolinium at same level as A1 showing an open-ring enhancement pattern. (A3) T2-weighted axial MRI at same level as A1 showing near-complete resolution of the lesion with residual brain biopsy defect. (Contributed by Dr. Claudia Lucchinetti.)