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Facial deformities in chronic yaws infection (rhinopharyngitis mutilans or gangosa)

The face of this woman showed the ravages of a disease known as yaws, a nonvenereal endemic syphilis, caused by the spirochete Treponema pallidum subspecies pertenue. The condition caused degenerative changes to the cartilage and bones that made portions of her face sink inward. (Source: Photography by Dr. JG Caldwell, Centers for Disease Control and Prevention, 1970. Public Health Image Library ID# 15980, Centers for Disease Control and Prevention, Atlanta, Georgia. Public domain.)

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  • Congenital rubella infection
  • Congenital toxoplasmosis infection
  • Maternal HIV infection
  • Maternal syphilis