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Distribution of congenital syphilis cases, by missed prevention opportunities--United States, 2022

Timely testing is performed 30 or more days before delivery. Late identification of seroconversion is a new reactive syphilis test fewer than 30 days before delivery after a nonreactive test earlier in pregnancy. Adequate treatment is receipt of a penicillin-based regimen, dosed and spaced appropriately for the stage of syphilis, and commenced 30 or more days before delivery. (Source: McDonald R, O'Callaghan K, Torrone E, et al. Vital signs: missed opportunities for preventing congenital syphilis--United States, 2022. MMWR Morb Mortal Wkly Rep 2023;72(46):1269-74. Public domain.)

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Associated Disorders

  • Congenital HIV infection
  • Congenital central nervous system infections
  • Congenital cytomegalovirus infection
  • Congenital herpes virus infection
  • Congenital infections
  • Congenital rubella infection
  • Congenital toxoplasmosis infection
  • Maternal HIV infection
  • Maternal syphilis