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Handwriting and drawings from motor examination pre- and post-DBS in cerebrotendinous xanthomatosis

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Handwriting and drawings of the dominant left upper extremity in a 42-year-old left-handed man with multiple cerebrotendinous xanthomatosis-related sequelae: motor examination pre-DBS placement and 6 months post-DBS VIM placement. The man's sequelae included developmental delay, cataracts, epilepsy, diabetes, chronic pancreatitis, anxiety, depression, parkinsonism, and postural or action tremor. His cerebrotendinous xanthomatosis-tremor was successfully treated with unilateral thalamic ventral intermediate nucleus (VIM) DBS (deep brain stimulation). (Source: Rich AM, Karakoleva EV, McInerney J, Farace E, De Jesus S. Cerebrotendinous xanthomatosis tremor successfully controlled post-ventral intermediate nucleus-deep brain stimulation: a case report. Front Neurol 2023;14:1243379. Creative Commons Attribution 4.0 International [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.)