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Normal cell layer replacement (photomicrograph)

The normal architecture of the cerebellar cortex has been replaced by hypertrophic neurons not typical of either normal Purkinje or normal granule cells. (Hematoxylin-eosin; x100) (Contributed by Dr. Laura Hair.)

Associated Disorders

  • Bannayan-Riley-Ruvalcaba syndrome
  • COLD syndrome
  • Cowden disease
  • Cowden syndrome
  • PTEN hamartoma tumor syndrome