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Molecular layer hypermyelination (photomicrograph)

High magnification of the molecular layer shows hypermyelination with thick fibers coursing parallel to the pial surface of the folium. (Luxol fast blue/periodic acid-Schiff reaction; x400) (Contributed by Dr. Laura Hair.)

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Associated Disorders

  • Bannayan-Riley-Ruvalcaba syndrome
  • COLD syndrome
  • Cowden disease
  • Cowden syndrome
  • PTEN hamartoma tumor syndrome