General Neurology
Hypopituitarism
May. 09, 2024
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Histopathologic features in eastern equine encephalitis (basal ganglia) (2)
Histopathologic features from a 5-year-old girl with eastern equine encephalitis in 2005, as part of a study of eastern equine encephalitis in Massachusetts and New Hampshire from 1970 to 2010. The postmortem samples of central nervous system tissue were obtained 10 days after the onset of symptoms. Eastern equine encephalitis virus colocalizes with areas of tissue injury in the brain. Immunohistochemistry of section adjacent to that shown in the previous figure; staining of the basal ganglia with eastern equine encephalitis immune ascites demonstrates foci of eastern equine encephalitis virus (arrow) that correspond with areas of tissue rarefaction in the previous figure (magnification ×12.5). (Source: Silverman MA, Misasi J, Smole S, et al. Eastern equine encephalitis in children, Massachusetts and New Hampshire, USA, 1970-2010. Emerg Infect Dis 2013;19[2]:194-201. Public domain.)