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Therapeutic approaches to self-injurious oral trauma in 19 patients with Lesch-Nyhan disease

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Frequency of therapeutic approaches to self-injurious oral trauma in 19 Italian patients with Lesch-Nyhan disease according to a structured telephone interview of their parents.

Key: (1) Tooth extraction. (2) Painkilling drugs for palliative rather than symptomatic relief. (3) Orthodontic appliances (eg, an acrylic maxillary device, designed and constructed with an occlusal plate raising the bite, or a soft resin mouth guard). (4) Dental re-contouring (ie, filing the teeth to make them less likely to cut the oral and perioral tissues). (5) Obstructive methods (eg, placing objects between the teeth to prevent biting lesions).

(Source: Isola G, Piccardo I, De Mari A, Alberti G, Migliorati M. Oral self-mutilation in Lesch-Nyhan patients: a cross-sectional study. J Clin Med 2022;11[20]:5981. (Creative Commons Attribution License [CC BY], https://creativecommons.org/licenses/by/4.0.)