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Biopsy photomicrograph in granulomatous cheilitis of Miescher (3)

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Photomicroscopy of a biopsy from a 27-year-old woman who presented with a 3-month history of unrelenting upper lip swelling. A few dilated lymphatics (green arrow) are seen adjacent to the granuloma along with mild perivascular lymphoplasmacytic cuffing (H&E x 40). The noncaseating granuloma is comprised of epithelioid cells, with a sprinkling of lymphocytes, histocytes (orange arrow), and multinucleated giant cells. (Source: Tummidi S, Nagendran P, Anthony ML, Ramani RJ, Shankaralingappa A, Gopinath H. Granulomatous cheilitis of Miescher: a rare entity. BMC Womens Health 2023;23[1]:118. Creative Commons Attribution 4.0 International [CC-BY 4.0] license, creativecommons.org/licenses/by/4.0. The image has been cropped from the original.)