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Osmotic demyelination after rapid correction of hyperosmolar hyperglycemia (1)

Osmotic demyelination in a 52-year-old woman after rapid correction of hyperosmolar hyperglycemia, axial diffusion-weighted imaging demonstrated restricted diffusion of the central pons (A and D) with correlate hypointense signal on ADC map (B and E). Correlate T2 FLAIR hyperintense signal (C and F) indicative of cytotoxic edema. (Source: Jain E, Kotwal S, Gnanaraj J, Khaliq W. Osmotic demyelination after rapid correction of hyperosmolar hyperglycemia. Cureus 2023;15[2]:e34551. Creative Commons Attribution license [CC BY], https://creativecommons.org/licenses/by/4.0.)

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Associated Disorders

  • Alcoholism
  • Extrapontine myelinolysis
  • Hyperosmolar hyperglycemic state
  • Hypokalemia
  • Malnutrition
  • Osmotic myelinolysis