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Worsening pontine hyperintensities on follow-up in osmotic demyelination syndrome (MRI)

In this 48-year-old man with the stuttering progression of neurologic deficits over several months, the follow-up T2-weighted image showed worsening pontine hyperintensities (thin red arrows). (Source: Olowoporoku IG, Digala LP, Attele DP. Central pontine myelinolysis: a case report of persistent hyperglycemia with normal serum sodium. Cureus 2022;14[9]:e29470. Creative Commons Attribution license [CC BY], https://creativecommons.org/licenses/by/4.0.)

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Associated Disorders

  • Alcoholism
  • Extrapontine myelinolysis
  • Hyperosmolar hyperglycemic state
  • Hypokalemia
  • Malnutrition
  • Osmotic myelinolysis