Sign Up for a Free Account

This is an image preview.
Start a Free Account
to view the full image.

Sign Up for a Free Account For information on discounts, see Plans & Pricing

  • Nearly 3,000 illustrations, including video clips of neurologic disorders.

  • Every article is reviewed by our esteemed Editorial Board for accuracy and currency.

  • Full spectrum of neurology in 1,200 comprehensive articles.

  • Listen to MedLink on the go with Audio versions of each article.

Young woman with vitamin B12 deficiency neurologic syndrome due to late-onset cobalamin C deficiency (serial MRI studies of brain and spinal cord)

At the time of diagnosis, brain MRI showed diffuse white matter lesions in both hemispheres (T2) with diffusion restriction (A and B), and spinal MRI revealed subacute combined degeneration of the cord (C). After 42 months of treatment, brain MRI showed cerebral atrophy and a regression of the white matter lesions (D and E) and spinal MRI showed regression of the spinal lesions (F). (Source: Ailliet S, Vandenberghe R, Schiemsky T, et al. A case of vitamin B12 deficiency neurological syndrome in a young adult due to late-onset cobalamin C [CblC] deficiency: a diagnostic challenge. Biochem Med [Zagreb] 2022;32[2]:020802. Creative Commons Attribution License, https://creativecommons.org/licenses/by/4.0.)

Related Article

Related Media

Associated Disorders

  • Alcohol-tobacco amblyopia
  • Cerebral vascular disease
  • Dementia
  • Depression
  • Developmental delay
  • Folate deficiency
  • Gastric resection
  • Glossitis
  • Imerslund-Grasbeck syndrome
  • Malabsorption
  • Megaloblastic anemia
  • Myelopathy
  • Optic neuropathy
  • Pernicious anemia
  • Polyneuropathy
  • Regional enteritis
  • Subacute combined degeneration of the spinal cord