Neuromuscular Disorders
Myoadenylate deaminase deficiency
Feb. 22, 2024
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Crude and stratified analyses with effect modification: the strength of the association varies by a third variable
In this case, the effect of vitamin D deficiency on the development of multiple sclerosis varies by age of exposure to vitamin D deficiency. Note, however, that effect modification does not necessarily imply causality: effect modification can operate with both causal and noncausal associations. (Contributed by Dr. Douglas J Lanska.)