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Partial callosal dysgenesis, interhemispheric glioependymal cyst, and cortical dysplasia (microscopic findings)

Shown are microscopic findings of cyst wall of a neonate with the syndrome of partial callosal dysgenesis, interhemispheric glioependymal cysts, and cortical dysplasia. Notice the presence of multiple papillary formations suggesting a differentiation into choroid plexus. (Illustrations from: Barth PG, Uylings HB, Stam FC. Interhemispheral neuroepithelial (glioependymal) cysts, associated with agenesis of the corpus callosum and neocortical maldevelopment. Childs Brain 1984;11:312-9.)

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Associated Disorders

  • Aicardi syndrome
  • Callosal dysgenesis
  • Neuronal heterotopia
  • Orofaciodigital syndromes, especially types I and II
  • Polymicrogyria
  • Trisomy-18