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Gamma-glutamyl cycle and enzyme deficiencies related to various diseases

Gamma-glutamyl cycle and enzyme deficiencies (highlighted in red) related to different diseases (highlighted in blue). Glutathione synthetase and glutathione synthetase deficiency are shown in the upper left of the figure. (Source: Wu X, Jiao J, Xia Y, et al. Case report: a Chinese patient with glutathione synthetase deficiency and a novel glutathione synthase mutation. Front Pediatr 2023;11:1212405. Creative Commons Attribution [CC BY] license.)

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