Sign Up for a Free Account

This is an image preview.
Start a Free Account
to view the full image.

Sign Up for a Free Account For information on discounts, see Plans & Pricing

  • Nearly 3,000 illustrations, including video clips of neurologic disorders.

  • Every article is reviewed by our esteemed Editorial Board for accuracy and currency.

  • Full spectrum of neurology in 1,200 comprehensive articles.

  • Listen to MedLink on the go with Audio versions of each article.

Pediatric epilepsy surgery plan for 9-year-old boy with pharmacoresistant focal epilepsy

Shown is an example of multidisciplinary approach to pediatric epilepsy surgery planning in a 9-year-old boy with pharmacoresistant focal epilepsy. Location of seizures, spikes, focal slowing, and fast ripples (high-frequency oscillations at 250 to 500 Hz) were mapped in a 3D reconstructed image of patient’s MRI and grid/strip electrodes (A). Pre-operative MRI, FDG-PET/MRI (B) and actual picture from the operation room (C) were used to create the 3D reconstructed image, and resection margin was determined based on discussion among the multidisciplinary epilepsy team. An extended temporo-parieto-occipital resection was performed based on widely distributed PET hypometabolism, epileptiform discharges, and slowing, although conventional MRI showed no anatomical abnormalities. Pathology showed gliosis with minimal cortical disorganization (our clinical suspicion was cortical dysplasia type I). (Contributed by Dr. Hiroki Nariai.)

Related Article

Related Media

Associated Disorders

  • Focal cortical dysplasia
  • Holoprosencephaly
  • Lissencephalies
  • Malformations of the brain
  • Polymicrogyria
  • Schizencephaly
  • Subcortical laminar heterotopia
  • Tuberous sclerosis complex