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Olfactory bulbs 12-year-old boy with hypoplasia (MRI)

Coronal T2-weighted MRI in 2 sections 4 mm apart of a 12-year-old boy with hypoplasia, but not total agenesis, of the olfactory bulbs. The brain was otherwise normal, and he did not have Kallmann syndrome, endocrinopathies, or neurologic deficits except for isolated anosmia. (Courtesy of Dr. Xing-Chang Wei, Department of Radiology and Imaging, Alberta Children’s Hospital.)

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Associated Disorders

  • Agenesis of the corpus callosum
  • Autism
  • CHARGE syndrome
  • Cerebellar dysfunction
  • Congenital heart disease
  • Diabetes mellitus
  • Disorders of eye movement
  • Hearing impairment
  • Hemimegalencephaly
  • Holoprosencephaly
  • Hypogonadotropic hypogonadism with anosmia
  • Ichthyosis
  • Kleefstra syndrome
  • Lissencephaly of TUBA1A mutation
  • Mental handicap
  • Pes cavus
  • Rubinstein-Taybi syndrome
  • Schizophrenia
  • Supernumerary olfactory bulbs
  • Synkinesis
  • Trisomy 13
  • Tuberous sclerosis complex
  • Waardenburg syndromes
  • Weaver syndrome