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UCMD: muscle biopsy

(A) Muscle biopsy (H&E) of a patient with Ullrich congenital muscular dystrophy shows a myopathic pattern with variation in fiber size, increased endomysial connective tissue, and fatty infiltration. (B) Immunohistochemistry shows positive laminin-alpha2 (merosin) staining. (Contributed by Dr. Goknur Haliloglu and Dr. Haluk Topaloglu.)

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Associated Disorders

  • Congenital muscular dystrophy
  • Merosin-positive congenital muscular dystrophy
  • Rigid spine syndrome