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Niemann Pick type C: foam cell

Bone marrow biopsy showing a “foam cell,” cholesterol-laden macrophage, from the patient with Niemann Pick type C from mutation in the NPC1 gene. (Courtesy of www.neuroophthalmology.ca. Contributed by Dr. Jason Barton.)

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Associated Disorders

  • Ataxia-telangiectasia
  • Progressive supranuclear palsy