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Chordoma

Chordomas are composed of fluffy vacuolated physaliferous cells (A touch prep, B H&E) that are mucinous (C, periodic acid-Schiff stain). (Contributed by Dr. Jason A Heth.)

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Associated Disorders

  • Li Fraumeni syndrome
  • Neurofibromatosis type 1
  • Neurofibromatosis type 2