Neuropharmacology & Neurotherapeutics
Edaravone
Apr. 23, 2021
This is an image preview.
Start a Free Account
to view the full image.
-
Nearly 3,000 illustrations, including video clips of neurologic disorders.
-
Every article is reviewed by our esteemed Editorial Board for accuracy and currency.
-
Full spectrum of neurology in 1,200 comprehensive articles.
-
Listen to MedLink on the go with Audio versions of each article.
Metabolic encephalopathy (suspected) (EEG)
This 64-year-old patient had undergone chemotherapy with melphalan and then total-body radiation prior to autologous stem cell transfusion for multiple myeloma. He was noted to have an altered mental status about 2 weeks later. His Glasgow Coma Score was 2/2/4 = 8. Neurologic examination showed no abnormalities other than the altered mental status. The patient was febrile, but no source of infection was found despite pan-culturing that included cerebrospinal fluid. Liver enzymes, ammonia, sodium, calcium, and magnesium were normal. MRI of the brain was also normal. The EEG showed moderate (mixed theta and delta activity) slowing and triphasic waves. The EEG was reactive to noxious stimulation. The EEG confirmed the encephalopathy and excluded depression or other non-neurologic cause for the mental status abnormality. The patient recovered. No follow-up EEG was performed. (Contributed by Dr. Jeffrey Nicholl and Dr. David Gloss.)