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"Watch out!” sign of subcallosal ischemia

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The "watch out!" sign is a neuroradiological sign proposed to rapidly recognize the lesional pattern of subcallosal ischemia or infarction. This is best visualized on axial diffusion-weighted imaging sequences in the acute phase (Holla VV, Pene SS, Rakesh Sharma MN. Acute amnestic syndrome: "watch out" for fornix infarct. Neurol India 2020;68[2]:498-9). Concomitant involvement in the territory of the recurrent artery of Heubner can occur in association with subcallosal artery ischemia. (Source: Mazzacane F, Ferrari F, Malvaso A, et al. Acute amnestic syndrome in fornix lesions: a systematic review of reported cases with a focus on differential diagnosis. Front Neurol 2024;15:1338291. Creative Commons Attribution 4.0 International [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.)