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Central pons hypointense signal in central pontine myelinolysis and hyperosmolar hyperglycemia (axial T1 MRI)

Axial T1-weighted sequence showing hypointense signal in the central pons consistent with central pontine myelinolysis in a 46-year-old man with hyperosmolar hyperglycemia. (Source: Qu HL, Sun XY, Dai YJ. Central pontine myelinolysis: a rare finding in hyperosmolar hyperglycemia. Front Neurol 2023;14:1216328. Creative Commons Attribution 4.0 International [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.) Figure edited by Dr. Douglas Lanska (cropping and removal of red color cast).

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Associated Disorders

  • Alcoholism
  • Extrapontine myelinolysis
  • Hyperosmolar hyperglycemic state
  • Hypokalemia
  • Malnutrition
  • Osmotic myelinolysis