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Chronic renal failure and severe restless legs syndrome (polysomnogram)

Periodic leg movements during wakefulness in a 50-year-old woman with chronic renal failure and severe restless legs syndrome. The movements occur every 17 seconds to 18 seconds and are more vigorous in the right leg than the left leg. Similar leg movements continued during stage 1 NREM and 2 NREM sleep. (Contributed by Dr. Michael Aldrich.)

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Associated Disorders

  • ALS
  • Alcohol use (lcohol abuse and its neurologic complications)
  • Amyotrophic lateral sclerosis
  • Ankylosing spondylitis
  • Antihistamines
  • Antinausea drugs
  • Antipsychotic drugs
  • Arborizing telangiectasia of the lower limbs
  • Attention deficit hyperactivity disorder
  • Brainstem strokes
  • Caffeine
  • Cardiovascular events
  • Chronic obstructive pulmonary disease
  • Cigarettes
  • Coffee
  • Congestive heart failure
  • Diabetes mellitus
  • Diphenhydramine
  • End-stage renal disease (Renal failure: neurologic complications)
  • Epilepsy
  • Essential tremor
  • Familial amyloid polyneuropathy
  • Fibromyalgia
  • Fluoxetine
  • Gastric disease or surgery
  • Haloperidol
  • Hemodialysis (Renal failure: neurologic complications)
  • Hepatitis C virus (Hepatitis viruses: neurologic complications)
  • Huntington disease
  • Hypersomnolence
  • Iron deficiency
  • Iron deficiency anemia
  • Isaacs syndrome (Neuromyotonia and myokymia)
  • Marburg virus (Viral hemorrhagic fevers: neurologic complications)
  • Metoclopramide
  • Migraine (Migraine: clinical aspects)
  • Multiple sclerosis (Multiple sclerosis: clinical aspects)
  • Myasthenia gravis
  • Nerve damage (Clinical evaluation of peripheral neuropathies)
  • Neuromyelitis optica spectrum disorders
  • Neuropathy (Clinical evaluation of peripheral neuropathies)
  • Nicotine
  • Obesity (Neurologic disorders associated with obesity)
  • Obstructive sleep apnea
  • Parkinson disease
  • Periodic limb movements
  • Peripheral neuropathy (Clinical evaluation of peripheral neuropathies)
  • Phenothiazine derivatives
  • Poliomyelitis
  • Polyneuropathy (Clinical evaluation of peripheral neuropathies)
  • Post-polio syndrome
  • Pregnancy (Pregnancy: neuromuscular complications)
  • Prochlorperazine
  • Rheumatoid arthritis: neurologic manifestations
  • SCA3 (Autosomal dominant hereditary ataxias)
  • SSRIs
  • Sertraline
  • Sleep deprivation (Insufficient sleep syndrome)
  • Sleep-related eating disorder
  • Spinal anesthesia (Epidural anesthesia)
  • Spinocerebellar ataxia 3 (Autosomal dominant hereditary ataxias)
  • Startle disease
  • Stiff-person syndrome
  • Tourette syndrome
  • Uremic neuropathy