Neuromuscular Disorders
Dermatomyositis
Feb. 28, 2024
This is an image preview.
Start a Free Account
to view the full image.
-
Nearly 3,000 illustrations, including video clips of neurologic disorders.
-
Every article is reviewed by our esteemed Editorial Board for accuracy and currency.
-
Full spectrum of neurology in 1,200 comprehensive articles.
-
Listen to MedLink on the go with Audio versions of each article.
Benign adult familial myoclonic epilepsy (clinical vignette)
Electroclinical and MRI features in a patient with BAFME. (A) Free-hand drawing showing cortical tremor; the drawing is perturbed by sudden, brisk jerks, highly suggestive of myoclonus. (B) Polygraphic recording showing mild, generalized paroxysmal activity and irregular, short-lasting electromyographic bursts, indicative of cortical myoclonus in the reciprocally antagonist muscles. (C) Jerk-locked averaging analysis shows a positive-negative potential, recognizable over the left centroparietal electrodes, preceding myoclonus about 30 ms (right wrist extensor muscle; number of triggers = 100). Somatosensory evoked potential (SEP) and C-reflex following electric stimulation of the right median nerve at wrist showing large N20 component and the complex N20-P25 of the left centro-parietal region (upper trace) followed from C-reflex in right flexor radialis carpi muscle (lower trace). (D) 1H-MR spectroscopy using a PRESS sequence (TR 1500 ms, TE 144 ms) showing abnormal spectral peak areas at 3.22 ppm corresponding to choline (location of the 8 cm3 voxel: right cerebellar hemisphere). (Contributed by Dr. Pasquale Striano.)