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Sensory testing with nylon monofilament

Ten-gram monofilament mounted in a handheld unit for protection of the filament. The device is placed perpendicular to the skin of the sole, and pressure is applied until the filament bends. Patient is asked to respond with eyes closed. The leprosy patients who are not able to feel the 10-gram monofilament are at risk of developing a plantar ulcer. (Contributed by Ravindra Kumar Garg.)

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Associated Disorders

  • Antineutrophil cytoplasmic autoantibodies in serum
  • Arthritis
  • Asymptomatic hepatic infiltration
  • Blood: hemolytic anemia, megaloblastic anemia
  • Bone: osteomyelitis, osteoporosis, osteoperiostitis
  • Dapsone hypersensitivity syndrome
  • Dapsone-related motor neuropathy
  • Eyes: uveitis, iritis, iridocyclitis, corneal ulcers, blindness
  • Generalized lymphadenopathy
  • Gynecomastia
  • High serum antiphospholipid antibodies
  • Kidney: nephrotic syndrome, renal amyloidosis, glomerulonephritis
  • Larynx: fibrosis of vocal cords, laryngeal ulcer, hoarseness of voice
  • Neuropathic osteoarthropathy
  • Nose: rhinitis, crusting, epistaxis, anosmia, nasal collapse
  • Palatal perforation
  • Plantar ulcer
  • Testes: acute orchitis, testicular atrophy, azoospermia, hypogonadism
  • Thalidomide neuropathy
  • Ulnar neuritis
  • Vitiligo