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Pathological changes in Susac syndrome (H&E × 100)

Brain histology at higher magnification shows microangiopathy with thickening of arteriolar wall and a sparse perivascular lymphocytic infiltrate (arrow). (Source: Bose S, Papathanasiou A, Karkhanis S, et al. Susac syndrome: neurological update [clinical features, long-term observational follow-up and management of sixteen patients]. J Neurol 2023;270[12]:6193-206. Creative Commons Attribution 4.0 International [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.)

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Associated Disorders

  • Cerebral microinfarcts
  • Deafness
  • Encephalopathy
  • Retinal arterial occlusion
  • Retinopathy