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Growth-hormone-secreting macroadenoma in a 21-year-old patient (MRI)

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(A) and (B) illustrate, respectively, coronal T1-weighted post-contrast and T2-weighted MRI images at diagnosis showing a large homogeneous pituitary mass with intra- and suprasellar extension, compression, and upward stretching of the optic chiasm. In addition, there is a cavernous sinus extension and internal carotid artery compression. (C) is a sagittal T1-weighted MRI image showing a large homogeneous pituitary mass with partial hyperattenuated margins. (Source: Sada V, Puliani G, Feola T, et al. Tall stature and gigantism in transition age: clinical and genetic aspects-a literature review and recommendations. J Endocrinol Invest 2024;47[4]:777-93. Creative Commons Attribution 4.0 International [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.)