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CDC laboratory recommendations for syphilis testing in the United States, 2024

Algorithms that can be applied to screening for syphilis with serologic tests. Abbreviations: CIA = chemiluminescence immunoassay; EIA = enzyme immunoassay; RPR = rapid plasma regain; TPPA = Treponoma pallidum particle agglutination; VDRL = Venereal Disease Research Laboratory. (Source: Papp JR, Park IU, Fakile Y, Pereira L, Pillay A, Bolan GA. CDC Laboratory Recommendations for Syphilis Testing, United States, 2024. MMWR Recomm Rep 2024;73(1):1-32. Public domain.)

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  • Congenital cytomegalovirus infection
  • Congenital herpes virus infection
  • Congenital infections
  • Congenital rubella infection
  • Congenital toxoplasmosis infection
  • Maternal HIV infection
  • Maternal syphilis