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Maternal syphilis rate, by trimester prenatal care began: United States, 2016-2022

(1) Significant increasing trend from 2016 to 2022 (p < 0.05). (2) Significant decreasing trend by timing of prenatal care for each year 2016 to 2022 (p < 0.05). Note: In 2022, 2.2% (77,228) of mothers did not receive prenatal care. (Source: National Center for Health Statistics, National Vital Statistics System, natality data file. Gregory EC, Ely DM. Trends and characteristics in maternal syphilis rates during pregnancy: United States, 2016-2022. NCHS Data Brief 2024;[496]:1-8. Public domain.)

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Associated Disorders

  • Congenital HIV infection
  • Congenital central nervous system infections
  • Congenital cytomegalovirus infection
  • Congenital herpes virus infection
  • Congenital infections
  • Congenital rubella infection
  • Congenital toxoplasmosis infection
  • Maternal HIV infection
  • Maternal syphilis