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Perioral papillomas due to early yaws infection

Anterior view of a child’s face showing numerous perioral papillomas, which developed as a result of the treponemal disease known as yaws. The first sign of yaws is the appearance of a painless papule, which grows into a papilloma. These large, early granulomatous lesions are highly infectious and display a yellow, crusty surface. (Source: Photography by Dr. JG Caldwell, Centers for Disease Control and Prevention, 1970. Public Health Image Library ID# 3832, Centers for Disease Control and Prevention, Atlanta, Georgia. Public domain.)

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