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Typical features of exencephaly on ultrasound

Two-dimensional ultrasound images at 17 weeks of gestation showing typical features of exencephaly (“Mickey Mouse” sign; white arrows). The calvarium is absent, and the brain is “floating” in the amniotic fluid. (Source: Sugiura T, Sato Y, Nakanami N, Tsukimori K. Prenatal sonographic image of sirenomelia with anencephaly and craniorachischisis totalis. Case Rep Obstet Gynecol 2018;2018:7058253. Creative Commons Attribution [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.)