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Proposed pathogenic mechanisms of Susac syndrome

Legend: TOX - thymocyte selection-associated high mobility group box; TCR - T cell receptor; CD8 - cluster of differentiate 8; TNF-α - tumor necrosis factor-alpha. (Source: Srichawla BS. Susac syndrome with livedo reticularis: pathogenesis and literature review. Cureus 2022;14[7]:e27352. Creative Commons Attribution 4.0 International [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.)

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