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Dissociation curves of carboxy-hemoglobin in absence of oxygen, at 38 degrees C and with various pressures of CO2

The different curves are almost identical if the scale on which the abscissae of each are plotted is altered by a suitable constant. Thus, the effect of varying proportions of CO2, (and presumably of acidity or alkalinity in general) is only to alter the scale on which the abscissae are plotted. Key: open circles--blood of CG Douglas; filled circles blood of John S Haldane (Sr.). (Source: Douglas CG, Haldane JS, Haldane JB. The laws of combination of haemoglobin with carbon monoxide and oxygen. J Physiol 1912;44(4):275-304.)

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