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Nerve impulse circuitry and the trajectory

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Cajal’s diagram outlining the circuitry and the trajectory of the nerve impulse (1894). The trajectory of the nerve impulse is shown by arrows. (A) Bipolar cells of the olfactory mucosa. (B) Olfactory glomeruli. (C) Mitral cells. (D) Grains. (E) External root (lateral olfactory tract). (F) Olfactory cortex. (a) Small tufted cell. (b) Main dendrite of a mitral cell. (c) Terminal branch of a grain. (e) Recurrent collaterals of a mitral cell. (g) Surface triangular cells of the olfactory cortex. (h) Epithelial cells of the nasal mucosa. (Source: Ramón y Cajal S. Croonian Lecture: la fine structure des centres nerveux. Proc R Soc Lond 1894;55:444-68. Instituto Cajal, Madrid, Spain. See: Figueres-Oñate M, Gutiérrez Y, López-Mascaraque L. Unraveling Cajal's view of the olfactory system. Front Neuroanat 2014;8:55. Creative Commons Attribution [CC BY] license, creativecommons.org/licenses/by/4.0.)