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Autophagic process divided into mechanistically different phases

The autophagic process can be divided into mechanistically different phases: initiation, vesicle formation (elongation and closure), autophagosome-lysosome fusion, and breakdown of the cargo. (Source: Coelho-Ribeiro B, Silva HG, Sampaio-Marques B, et al. Inflammation and exosomes in Fabry disease pathogenesis. Cells 2024;13[8]:654. Adapted from: Chiramel AI, Brady NR, Bartenschlager R. Divergent roles of autophagy in virus infection. Cells 2013;2[1]:83-104. Creative Commons Attribution 4.0 International [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.)

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