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Progressive meningeal disease in acute lymphoblastic leukemia (MRI) (3)

Because of progressive neurologic decline, this patient underwent for the third time. Hypointensity was increased on T1-weighted images, and sulcal and meningeal enhancement was evident. There was evidence of worsening of the abnormalities previously noted on FLAIR and diffusion-weighted imaging and a new area of restricted diffusion in the left thalamus. (Contributed by Dr. Jon Glass.)

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