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Muscular hypertrophy of the lower extremities in Hoffmann syndrome (MRI)

MRI of a 61-year-old man with Hoffmann syndrome shows muscular hypertrophy of the lower extremities but no signs of myositis or myopathy (ie, no gadolinium enhancement, edema, or fatty degeneration). (Source: Winter S, Heiling B, Eckardt N, Kloos C, Axer H. Hoffmann's syndrome in the differential workup of myopathic complaints: a case report. J Med Case Rep 2023;17[1]:473. Creative Commons Attribution 4.0 International [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.)

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Associated Disorders

  • Endocrine ophthalmopathy
  • Graves disease
  • Graves ophthalmopathy
  • Hashimoto thyroiditis
  • Hoffmann syndrome
  • Hyperthyroid myopathy
  • Hypothalamic dysfunction
  • Hypothyroid myopathy
  • Kocher-Debre-Semelaigne syndrome
  • Pituitary dysfunction
  • Thyroid-associated ophthalmopathy
  • Thyrotoxic myopathy
  • Thyrotoxic ocular myopathy