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Imaging abnormalities in new-onset refractory status epilepticus (NORSE) and febrile infection-related epilepsy syndrome (FIRES) of unknown etiology

(A) Bilateral FLAIR hyperintensities in the claustrum on MRI 12 days into the acute phase of FIRES of unknown etiology in a 33-year-old patient. (B) Disappearance of these hyperintensities on a 6-month follow-up MRI. (C) Unilateral FLAIR hyperintensity in the left claustrum on MRI 14 days into the acute phase of NORSE of unknown etiology in a 21-year-old patient. (D) Disappearance of this hyperintensity on a 4-month follow-up MRI. (Contributed by Dr. Nicolas Gaspard.)

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Associated Disorders

  • Genetic encephalopathy
  • Infectious encephalitis
  • Paraneoplastic encephalitis
  • Postinfectious disorders
  • Primary autoimmune encephalitis