Epilepsy & Seizures
Landau-Kleffner syndrome
Jul. 26, 2021
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Toll Free (U.S. + Canada): 800-452-2400
US Number: +1-619-640-4660
Support: service@medlink.com
Editor: editor@medlink.com
ISSN: 2831-9125
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This complex lipid can be viewed as a polar headgroup consisting of a glycerol backbone. C1 and C3 are esterified to the phosphate groups of glycerol phosphatide (diacylglycerol phosphate) on each side, each carrying two hydrophophobic acyl-chains. The composition of the 4 side chains is variable. The drawn structure carries 4 linoleic chains, the predominant composition in various tissues, including skeletal and heart muscle. The side chain composition is regulated by tafazzin, a transacylase, deficient in Barth syndrome. The polar headgroup is coloured in cyan, and the apolar tail region in green. (Contributed by Dr. Peter Barth.)