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Emergences of cVDPV2 in 2016-2023 after the tOPV-to-bOPV switch linked to OPV use

The figure depicts the use of Sabin OPV (mOPV2 and tOPV) for outbreak response and introduction of nOPV2 in March 2021. The data are from July 1, 2016 to December 31, 2023.

Abbreviations: cVDPV2, type 2 circulating vaccine-derived type 2 monovalent oral poliovirus vaccine; tOPV, trivalent oral poliovirus vaccine; bOPV, bivalent oral poliovirus vaccine; mOPV2, type 2 monovalent oral poliovirus vaccine; nOPV2, novel type 2 oral poliovirus vaccine.

(Source: Lopez Cavestany R, Eisenhawer M, Diop OM, Verma H, Quddus A, Mach O. The last mile in polio eradication: program challenges and perseverance. Pathogens 2024;13[4]:323. Based on a figure from: Bandyopadhyay AS, Zipursky S. A novel tool to eradicate an ancient scourge: the novel oral polio vaccine type 2 story. Lancet Infect Dis 2023;23[2]:e67-71. Creative Commons Attribution 4.0 International [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.)

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  • Infantile paralysis
  • Nonparalytic polio
  • Paralytic polio
  • Polioencephalitis
  • Post-polio progressive muscular atrophy
  • Post-polio syndrome
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