Comparison of the three types of connections in functional connectivity networks

The mean strength of the three connections between patients with presbycusis and healthy controls were compared using a two-sample t-test. (A) In LOFC networks, no significant intergroup differences were observed in the mean strength of the three connections. (B) In HOFC networks, the mean strength of rich-club connections in patients with presbycusis was significantly higher than in healthy controls (p < 0.05). *indicates significant intergroup difference with P < 0.05. Abbreviations: LOFC, low-order functional connectivity; HCs, healthy controls; HOFC, high-order functional connectivity. (Source: Xu Y, Li X, Yan Q, et al. Topological disruption of low- and high-order functional networks in presbycusis. Brain Commun 2024;6[2]:fcae119. Creative Commons Attribution 4.0 International [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.)