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Rhabdomyolysis diagnostic workup

Suggested workup scheme for cases of rhabdomyolysis. (Zutt R, van der Kooi AJ, Linthorst GE, Wanders RJ, de Visser M. Rhabdomyolysis: review of the literature. Neuromuscul Disord 2014;24(8):651-9.)

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Associated Disorders

  • Aconitase deficiency
  • Acute renal failure
  • Acute respiratory distress syndrome
  • Carnitine palmityl transferase deficiency
  • Disseminated intravascular coagulation
  • Dystrophin deficiency
  • Endocrine disorders
  • Gastrointestinal disorders
  • Glycogen storage diseases
  • Influenza
  • Lactate dehydrogenase deficiency
  • Legionnaire disease
  • Lipid myopathies
  • Long-chain acyl CoA dehydrogenase deficiency
  • Muscle glycolytic defect
  • Phosphofructokinase deficiency
  • Phosphoglycerate kinase deficiency
  • Phosphoglycerate mutase deficiency
  • Phosphorylase deficiency
  • Renal tubular acidosis
  • Short-chain L-3 hydroxyacyl CoA dehydrogenase deficiency
  • Succinate dehydrogenase deficiency
  • Toxic shock syndrome
  • Trifunctional protein deficiency
  • Very long-chain acyl-CoA dehydrogenase deficiency