Neuro-Oncology
Neurofibromatosis 1
Jan. 15, 2024
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Creutzfeldt-Jakob disease (MRI)
There is diffuse cortical diffusion restriction involving the right cerebral hemisphere, predominantly in the right parietal, occipital, and temporal lobes, as well as the right caudate and putamen. The patient was a 55-year-old male with a 6-week history of feeling foggy, dizzy, and unsteady. On examination, there was confusion, myoclonus, ataxia, and corticospinal tract signs. The EEG showed intermittent frontal predominant generalized periodic sharp wave complexes with triphasic morphology at 1.5-2 hz. The RT-QuIC test on the CSF was positive. (Contributed by Dr. Raymond Roos.)