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Infratentorial superficial siderosis in a 77-year-old woman (MRI)

MRI in a 77-year-old woman with progressive hearing loss, gait ataxia, visual disturbances, and visual hallucinations over 6 months due to classical infratentorial superficial siderosis. Axial T2*-GRE (a-f) showing superficial siderosis of the upper cervical spinal cord (a, arrow), cranial nerve VIII but sparing cranial nerve VII (b; arrowhead, arrow), the cerebellum and mesencephalon (c, d; arrow), the medial Sylvian fissure (e, arrow) and of the medial occipital lobes (f, arrow).

Abbreviation: T2*-GRE multi-echo gradient recalled echo T2*-weighted imaging (Tang MY, Chen TW, Zhang XM, Huang XH. GRE T2∗-weighted MRI: principles and clinical applications. Biomed Res Int 2014;2014:312142).

(Source: Weidauer S, Neuhaus E, Hattingen E. Cerebral superficial siderosis: etiology, neuroradiological features and clinical findings. Clin Neuroradiol 2023;33[2]:293-306. Creative Commons Attribution 4.0 International [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.)

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Associated Disorders

  • Ataxia
  • Peripheral vestibular disorders
  • Sensorineural hearing loss
  • Subarachnoid hemorrhage